NEFM antibody (C-Term)

Catalog No. ABIN363322

This Rabbit Polyclonal antibody specifically detects NEFM in WB, IHC, IF and ICC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for NEFM antibody (C-Term) (ABIN363322)

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEFM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-NEFM Antibody

Binding Specificity: C-Term

Specificity: Reacts with the evolutionarily conserved extreme C-terminal region of the medium neurofilament subunit (~145-170 kDa)

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Cross reacts with NF-M from all mammals, birds and reptiles tested to date, including human, cat, rat, mouse, cow and pig.

Purification: Antiserum

Immunogen: Recombinant C-terminal segment of rat NF-M

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB1:5000-1:10000 ICC/IF1:500-1:1000 IHC1:1000-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Target Details for NEFM

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Alternative Name: Neurofilament Medium Chain (NF-M)

Background: Belongs to the intermediate filament family. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.

Pathways: Brown Fat Cell Differentiation